International review of probiotic supplements containing I.31 (a 3-strain probiotic blend) found only 4 products passed all relevant criteria for IBS symptom management.

Last updated 4 October 2024 | Results reviewed by Daniel Keats RDN

1.1 Passed key criteria

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1.2 Table of results

Order of Results: Product names are listed alphabetically within each category.

Explanation of criteria

  1. Transparent Formula: The supplement’s ingredients and their amounts are openly labeled, not hidden behind proprietary blends. This transparency is essential for us to verify that it meets the studied dose requirements.
  2. Studied Dose: For I.31 in IBS populations, the effective dose is 3 to 6 billion CFUs per day. Any product that delivers this specific dose in one or more servings meets this criterion.
  3. IBS RCT Probiotics Only: The product contains only probiotic strains that have been studied in IBS populations through randomized, placebo-controlled clinical trials. No other active ingredients are included, as unstudied additives may alter efficacy.
  4. Third-Party Tested CFUs: The manufacturer has submitted the product for third-party testing to verify both the CFU count (amount of probiotics in finished product) and has published the results on their website.
  5. Availability: Indicates where the product can be purchased. Please note that consumers worldwide can often access USA and UK products using a forwarding service.

1.3 Summary

  • We searched the entire web to find and evaluate products containing I.31.
  • 8 product were found containing I.31.
  • 4 products failed because they contained additional active ingredients that are not probiotics studied in randomized controlled trials for IBS populations.
  • The other 4 products meet all the key criteria outlined above: transparent formula, deliverable at studied dose, and only contains IBS-RCT probiotic strains.
  • Of these, no products published third-party testing results on their website.

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