Find a high quality probiotic that is formulated & dosed according to clinical studies for IBS patients

1) Results below are sorted based on 1) Global IBS relief and 2) evidence quality.

2) Symptom improvement results are taken from IBSprobiotics.org – a research project reviewing over 40 probiotic strains/blends across 69 randomized placebo-controlled clinical trials.
See the full list of results, as well as explanations about efficacy size improvements, evidence quality ratings and methodology.

How the featured strains & blends fit together based on genus, species & strain

To understand probiotic strains, it’s important to know how bacteria are named: the genus (e.g. Bacillus) groups organisms based on general similarities, the species (e.g. coagulans) narrows it down to those with specific shared features, and the strain (e.g. Unique IS-2 MTCC 5260) further divides species into subgroups based on distinct properties. This classification helps in identifying and categorizing probiotic strains more precisely.

PROBIOTIC NAME BACILLUS LACTOBACILLUS BIFIDOBACTERIUM STREPTOCOCCUS OTHER
Unique IS-2 coagulans ATCC PTA-11748, MTCC 5260
Lactospore coagulans MTCC 5856
Bio-Kult subtilis PXN21 acidophilus PXN35 bulgaricus PXN39 casei PXN37 plantarum PXN47 rhamnosus PXN54 helveticus PXN45 salivarius PXN57 bifidum PXN23 breve PXN25 infantis PXN27 longum PXN30 thermophilus PXN66 Lactococcus lactis PXN63
DDS-1 acidophilus DDS-1
LGG rhamnosus GG (LGG)
ATCC SD5221 x LAFT1 acidophilus ATCC SD5221 acidophilus helveticus LAFT1
I.31 plantarum CECT7484 plantarum CECT7485 Pediococcus acidilactici CECT7483
Symprove acidophilus NCIMB 30175 Enterococcus faecium NCIMB 30176 Lacticaseibacillus rhamnosus NCIMB 30174 Lactiplantibacillus plantarum NCIMB 30173
BGN4 x AD011 x AD031 x IBS041 acidophilus AD031 casei IBS041 bifidum BGN4 lactis AD011
De Simone acidophilus DSM 24735/SD5212 bulgaricus DSM 24734/SD5210 paracasei DSM 24733/SD5218 plantarum DSM 24730/SD5209 longum DSM 24736/SD5219 infantis DSM 24737/SD5220 breve DSM 24732/SD5206 thermophilus DSM 24731/SD5207
Probio-Tec acidophilus LA-5 bulgaricus LBY-27 lactis BB-12 thermophilus STY-31
UABla-12 lactis UABla-12